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Syeni isn't a traditional salon and spa - we're a place where holistic wellness and beauty are combined to create rejuvenation.  Our highly trained team is dedicated to making every one of our clients feel absolutely cared for, offering a simple selection of salon and spa services for both men and women.  When you visit us, you'll find guests sipping herbal teas and honey while learning about the benefits of various medicinal herbs.  You'll even see us using our own line of products inspired by plant biology.  Whether you're visiting us for a massage, a facial, or a new hairstyle, you'll always have a fresh new experience to look forward to. 

Where old world Mediterranean style and the antiquity of the Tobacco & Mule Exchange come together. Located in the Downtown Historic Apex. The exposed beams, ceilings, and wooden floors take you to times past. The furnishings and features blend historic and modern into a very inviting atmosphere.

All of the traditional services are offered for men and women, but with an added Twist, which makes this Salon & Spa so unique

Pure relaxation awaits you at Syeni Salon & Spa. Come and experience the old world charm blended with local hometown history – Downtown Historic Apex, North Carolina

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If you have any questions, comments or concerns.

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To Ensure an incredible Experience

Please arrive 15 minutes before your scheduled appointment time. Unfortunately, late arrivals will not receive an extension on treatments and will be responsible for full service fees. Our scheduling times reflect actual treatment times. We cannot be responsible for valuables and suggest that you refrain from bringing them to the spa. Out of consideration for our other guests, please mute cell phones in the spa. All prices subject to change. Please note that quoted prices do not include gratuities.

Cancellation and Booking

Cancelling an appointment with 24 hours notice will not result in any charges.We reserve the right to charge 50% of the total scheduled services for a same day cancellation of an appointment unless we are able to fill the appointment time. We reserve the right to charge up to 50% of the scheduled services that are a “no call, no show” appointment. Discounts may be available for groups of 5 or more people. 18% gratuity will be added in addition to all groups with 5 or more people.



(919) 387-4166



225 N. Salem St. Suite 103
Tobacco & Mule Exchange
Apex, NC 27502


Sun & Mon Appointment Only

Tues - Fri 9a–6:30p

Sat 9a-5p


Please remember that your appointment time is reserved especially for you. This policy has been put in place because both your time and our time are valuable. By giving us 24 hours’ notice, we can reschedule your appointment and possibly free up your original time for another client.

Thank you for your understanding! We will require a credit card number on file to reserve your appointment. This credit card number will be securely stored in our system and will not be charged except per our cancellation policy.